You can work with Panorama if you’re on a next gen project. You’ll be able to use all of the features - just like while working with the standard projects.
There are just two things that are currently not possible:
moving issues between different Epics within a panorama
if you create a new issue under Epic in a panorama, you won’t be able to delete them (Jira’s API doesn’t allow add-ons yet to do it in next-gen projects)
We’ll inform you when these two issues will be resolved.